Votrin, S. I. and Bolevich, S. B. and Vorobiev, S. I. and Orlova, A. S. and Bolevich, S. S. and Tachieva, B. I. and Korsakov, D. Yu. (2018) Elimination of hypoxia in acute autoimmune intravascular hemolysis with perfluorocarbon blood substituting emulsion in experiment. Sechenov Medical Journal (2). pp. 5-13.
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Abstract
Autoimmune intravascular hemolysis is an acute process of destruction of erythrocytes in the bloodstream, as a result of the action of antibodies and complement on the erythrocyte membrane. Toxins, as well as the products released by hemoparasites, can cause damage to the erythrocyte membrane, followed by activation of autoimmune reactions and manifestation of acute autoimmune intravascular hemolysis. The use of blood-substituting emulsion of perfluoroorganic compounds in anemia caused by acute autoimmune intravascular hemolysis is especially relevant in presence of contraindications to the use of donor erythrocytes. The use of artificial oxygen carriers makes it possible to provide organs and tissues with oxygen without inducing aggravation of the autoimmune process.
Item Type: | Article |
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Subjects: | OA Library Press > Medical Science |
Depositing User: | Unnamed user with email support@oalibrarypress.com |
Date Deposited: | 04 Mar 2023 11:53 |
Last Modified: | 23 May 2024 06:39 |
URI: | http://archive.submissionwrite.com/id/eprint/338 |